Percutaneous transluminal septal myocardial ablation or PTSMA is a minimally invasive procedure performed in the cardiac catheterisation laboratory to reduce the overgrowth of heart muscle associated with hypertrophic obstructive cardiomyopathy. PTSMA involves an injection of alcohol into the septal branch of the left anterior descending artery resulting in a intentional and controlled “infarction” of the area with thinning and scarring of the heart muscle and resultant reduction in pressure and improved patient symptoms.