Associate Professor Sarah Hope, BSc Med Sci (Hons), MBChB, MRCP (UK), MRCPCH, PhD, FRACP, FCSANZ

Associate Professor Sarah Hope is Head of Paediatric Cardiology Services, MonashHeart and Monash Children’s, Southern Health, and an active member of Monash Cardiovascular Research Centre. She has more than 15 years experience in Paediatric Cardiology and also has experience in the management of adult congenital heart disease.

Associate Professor Sarah Hope undertook her undergraduate medical training at the University of Edinburgh, gaining postgraduate experience in Paediatrics and Paediatric Cardiology in and around Edinburgh, Oxford, Harefield and Southampton in the United Kingdom prior to coming to Melbourne. She completed her PhD in the Monash Cardiovascular Research Centre and undertook further training in Paediatric Cardiology at the Royal Children’s Hospital and Monash Medical Centre.
 

Qualifications - Edinburgh University

• Bachelor of Medical Science  BSc(Med Sci)(Hons) 1987
• Bachelor of Medicine, Bachelor of Surgery MB ChB 1989

Qualifications - Monash University

• Doctor of Philosophy Ph.D. 2004

Qualifications

• Level 3 SCCT 2008
  

Professional registrations

• Registered medical practitioner, UK
• Registered medical practitioner, Australia   

Scientific and professional societies

• Fellow of the Royal Australasian College of Physicians
• Member of the Royal College of Physicians (UK)
• Fellow of the Cardiac Society of Australia and New Zealand
• Member of the Royal College of Paediatrics and Child Health
• Member of the International Society for Vascular Health
  

• Associate Professor, Department of Medicine, Monash University
• Head of Paediatric Cardiology, MonashHeart and Monash Children’s, Southern Health
• Senior Researcher, Monash Cardiovascular Research Centre, MonashHeart, Southern Health
• Member, Senior Medical Staff, Southern Health, Melbourne, Australia

• 1st prize clinical poster, Southern Health Research Week.
  LDL and Total Cholesterol Levels are Associated with Decreased, and Statin Use with Increased, Levels of Activin A in Patients with Coronary Artery Disease, 2007
• Chairman’s Prize, Borders Clinical Club, for the presentation of a paper on 'The Foetal Valproate Syndrome', 1994
• Ashdown Scholarship, awarded by Hertfordshire County Council for outstanding academic achievement at First Year Sixth level, 1982

• Invited Faculty for 5th World Congress of Paediatric Cardiology and Cardiac Surgery
• Member of the Editorial Steering Committee for the Annual Research Report for Southern Health and partners at the Monash Health Research Precinct
• Member of the Australasian Regional Committee of the International Society of Vascular Health

Main research endeavours include:

• Vascular function and arterial mechanical properties and associations with cardiovascular risk
• The applicability of arterial transfer functions
• New methods for the assessment of vascular function and arterial mechanical properties
• Assessment of neonatal cardiovascular physiology
• Novel applications of cardiac computed tomography

Theses

Hope SA.    Factors Influencing the Differentiation of Mouse Embryonal Carcinoma Cells in Tissue Culture. Bachelor of Medical Science (Hons), University of Edinburgh, 1987.

Hope SA.    Arterial Pressure Waves: Waveform Characteristics, Their Associations and Factors Influencing Their Propagation. Doctor of Philosophy (Medicine), Monash University, 2004

Top 10 peer reviewed articles in scientific journals

1.    O’Driscoll DM, Horne RS, Davey MJ, Hope SA, Walker AM, Nixon GM. The heart rate response to spontaneous arousal from sleep is reduced in children with Down Syndrome referred for evaluation of sleep-disordered breathing. Am J Physiol Heart Circ Physiol 2010;298:H986-90.

2.    Nelson AJ, Worthley SG, Cameron JD, Willoughby SR, Piantadosi C, Carbone A, Dundon BK, Leung MC, Hope SA, Meredith IT, Worthley MI. Cardiovascular magnetic resonance-derived aortic distensibility: validation and observed regional differences in the elderly. Journal of Hypertension 2009;27:535-42.

3.    Hope SA, Antonis PR, Adam D, Cameron JD, Meredith IT. Pulse wave velocity but not central aortic augmentation index is associated with coronary artery disease extent and severity. Journal of Hypertension 2007;25:2105-09.

4.    Hope SA, Meredith IT, Tay D, Cameron JD. “Generalisability” of radial-aortic transfer function for the derivation of central aortic waveform parameters. Journal of Hypertension 2007;25:1812-20.

5.    Clarke HG, Hope SA, Byers S, Rodgers RJ. Formation of ovarian follicular fluid may be due to the osmotic potential of large proteoglycans. Reproduction 2006;132:119-131.

6.    Hope SA, Tay DB, Meredith IT, Cameron JD. Waveform dispersion, not reflection may be the major determinant of aortic pressure wave morphology. Am J Physiol Heart Circ Physiol 2005;289:H2497-502.

7.    Hope SA, Tay DB, Meredith IT, Cameron JD. Use of arterial transfer functions for the derivation of central aortic waveform characteristics in subjects with Type 2 diabetes mellitus. Diabetes Care 2004;27:746-751.

8.    Hope SA, Tay DB, Meredith IT, Cameron JD. Use of Arterial Transfer Functions for the Derivation of Aortic Waveform Characteristics. Journal of Hypertension 2003;21:1299-305.

9.    Hope SA, Meredith IT, Farouque HMO, Worthley SG, Plunkett JC, Balazs ND. Time Course of Plasma Adhesion Molecules in Acute Coronary Syndromes. Coronary Artery Disease 2002;13:215-221.

10.    Hope SA, Tay DB, Meredith IT, Cameron JD. Comparison of Generalized and Gender-Specific Transfer Functions for the Derivation of Aortic Waveforms. Am J Physiol Heart Circ Physiol 2002;283:H1150-H1156.

Recent invited international and national participation

Faculty for the Society of Cardiovascular CT Annual Scientific, Typical problems after surgery for congenital heart disease and their evaluation and follow up by CT, July 2010.

Faculty World Congress of Paediatric Cardiology and Cardiac Surgery, July 2009.

Long term follow up of coronary artery patency post Kawasaki disease. General Paediatric Update meeting, Monash Medical Centre, June 2008.

From the Foetus to the Grave. Atherosclerosis and vascular function: a paediatric perspective. Monash/Casey General Practice Group, August 2008.

Vascular health – large vessels are most important. Australasian regional meeting of the International Society of Vascular Health, August 2008.